Immunostimulatory conventional dendritic cells evolve into regulatory macrophage-like cells
نویسندگان
چکیده
منابع مشابه
Immunostimulatory conventional dendritic cells evolve into regulatory macrophage-like cells.
Dendritic cell (DC) homeostasis in peripheral tissues reflect a balance between DC generation, migration, and death. The current model of DC ontogeny indicates that pre-cDCs are committed to become terminal conventional DCs (cDCs). Here, we report the unexpected finding that proliferating immunostimulatory CD11c(+) MHC class II(+) cDCs derived from pre-cDCs can lose their DC identity and genera...
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ژورنال
عنوان ژورنال: Blood
سال: 2012
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2011-11-392894